Bilberry fruit [Vaccinium myrtillus L]
Bilberry extract is used to treat Retinopathy, Cataracts, Macular degeneration, Retinitis pigmentosa, Hemorrhagic retinopathy. Bilberry anthocyanins regenerate rhodopsin are indicated in the treatment of poor night vision and cataracts. Bilberry is also used to treat microcirculatory disorders which include varicose veins, atherosclerosis, venous insufficiency.
MECHANISM OF ACTION:
- Inhibits enzymatic cleavage of collagen by the enzymes secreted by leucocytes during Inflammation.
- By inhibiting retinal phosphoglucomutase and glucose-6-phosphatase it confers retinal protection.
- Reduces microvascular impairments due to ischemic reperfusion injury, with preservation of endothelium, attenuation of leukocyte adhesion and improvement of capillary perfusion.
- Produces dose dependent inhibition of platelet aggregation and clot retraction.
- Decreases basement membrane collagen hydrolysis by significantly reducing permeability of the blood-brain barrier and increases recovery rate of the BBB caused by permeability-increasing agents.
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