Ketoconazole 2% (20rng/gm): cream preparation.
Ketoconazole 2o/o delivers long lasting & powerful relief, and exhibits significant improvement in seborrheic dermatitis.
Ind: Treatment and prophylaxis of infections in which the yeast Malassezia (previously called Pityrosporum) is involved, such as- Dandruff (pityriasis capitis), Pityriasis versicolor (localized), inflammatory skin condition with greasy, red & scaly areas (seborrhoeic dermatitis).
The clinical effect of ketoconazole 2% cream is 95% improvement.C/I: Known hypersensitivity to ketoconazole or any of the excipients.
S/E: A local burning sensation, itching, or contact dermatitis (due to irritation or allergy), may occur on exposed areas.
Precautions: In patients who have been on prolonged treatment with topical corticosteroids, it is recommended that the steroid therapy be gradually withdrawn over a period of 2 to 3 weeks, while using Ketoconazole 2% cream to prevent any potential rebound effect.
Pregnancy & lactation: Since ketoconazole is not absorbed through the skin after topical application, it is not contraindicated in pregnancy and lactation.
Dosage & appli: Tinea pedis: Cream should be applied to the affected areas twice daily.
Treatment should be continued 1 week for mild infections & for severe/extensive infections, should be continued until a few days after all sign and symptoms have  disappeared.
For other infections: Cream should be applied to the affected areas once or twice daily, depending on the severity of the infections, such as-
- Tinea versicolor- 2-3 weeks.
- Tinea corporis- 3-4 weeks.
The diagnosis should be reconsidered if no clinical improvement is noted after 4 weeks. Severe/extensive infections- Treatment should be continued until a few days after all sign and symptoms have disappeared.
15gm tube: 50.00 MRP