Pentaxim: A pentavalent combined antibacterial and antiviral vaccine comprising diphtheria, tetanus, acellular pertussis and inactivated poliomyelitis vaccine, adsorbed and hemophilus influenzae type b conjugate vaccine. It is available as powder and suspension for suspension for injection in prefilled syringe. Comp: Each single dose of 0.5ml ampoule con¬tains: Diphtheria toxoid >30 iu; Tetanus toxoid >40 iu; Bordetella pertussis antigens toxid 25mcg; Filamentous hemagglutinin 25mcg; inac¬tivated type 1 poliomyelitis virus D antigen 40 units, inactivated type 2 poliomyelitis virus D antigen 8 units, inactivated type 3 poliomyelitis virus D antigen 32 units; Hemophilus influenzae type b polysaccharide (conjugated to tetanus protein) lOmcg,
Ind: This vaccine is indicated in the combined prevention of invasive infections caused by hemophilus influenzae type b (meningitis, sep¬ticemia, cellulitis, arthritis, epiglottitis etc.), diphtheria, tetanus, pertussis and poliomyelitis- for primary vaccination in infants over 4 months of age, for booster vaccination, one year after the primary vaccination during the second year of life. This vaccine does not protect against infec¬tious disease due to other types of hemophilus influenzae or against meningitis caused by other micro-organisms.
C/I: 1. Progressive encephalopathies, with or without convulsions. 2. Major reaction(s) within 48 hours of a previous vaccine injection (such as- fever greater than or equal to 40°C, persistent crying syndrome, febrile or afebrile convulsions, hypotonic hyporesponsive episodes), in such cases, vaccination should be completed with a vaccine which does not contain the pertussis vac¬cine. 3, Immediate hypersensitivity reactions fol¬lowing a previous injection (generalized urticaria, Quincke's oedema, anaphylactic shock). 4. Hyp¬ersensitivity reactions to active substances, excip¬ients, neomycin, streptomycin or polymyxin B. S/E; Precautions & warnings: Please see manufacturer’s literature. Dosage & admin: Primary vaccination: The course of vaccination is 3 injections at one or two month intervals from 2 months of age. Booster vaccination: 1 injection one year after the primary vaccination, generally between 16 and 18 months.
Method of administration: This vaccine should be administered intramuscularly. The prefered injection site is the anterolateral surface of the thigh (middle third).
Instructions for use & handling: Reconstitute the solution by injection of combined diphtheria, tetanus, acellular pertussis and poliomyelitis vaccine in the powder vial of hemophilus influenzae type b vaccine. Shake until complete dissolution of the powder. The whitish-turbid aspect of the suspension after reconstitution is normal. The vaccine must be injected immediactely after reconstitution.
Storage: Store at 2°C to 8*C (in a refrigerator). Do not freeze.
Note: For further information, please consult manufacturer’s literature.
0.5ml prefilled syringe x l’s pack: 1390.63 MRP