The Verorab is a purified Vero-rabies vaccine (PVRV) presented in freeze-dried form, as a single vaccinating dose of the inactivated virus. The virus is produced on VERO cell cultures. These are heteroploid cells, derived from a monkey kidney cell culture (cercopithecus aethiops) and adapted for mass cultivation on microcarriers. The vaccine is reconstituted with
0.5ml of solvent (sodium chloride solution) at the time of use.
Dosage & admin: Adults & children:
/. Preventive action or pre-exposure prophylaxis: 3 injections of 0.5ml vial on D-0, D-7, D-28.
Booster-1 year later 1 injection & then every five years 1 injection if the risk persists (a variation of a few days is not important).
2. Post-exposure treatment or immunization:
a)    If the subject has not been vaccinated- after being bitten by an animal with rabies or suspected rabies, 5 s.c or i.m injections (each dose 0.5ml) should be given on days D-0, D-3, D-7, D-14, D-28.
b)    If the subject has had preventive vaccination those vaccinated less than one year ago- give a booster on day: D-O.
Subjects vaccinated more than one year ago depending on the seriousness of the case give: First booster on day D-O
Second booster on day D-3 Third booster on day D-7
c)    Finally, in cases of very severe biting, on day D-O, give additional treatment of 20
1.    u/kg of human antirabies immunoglobulin; or 40 i.u/kg of a purified antirabies serum of equine origin.
Note: Dosage for children is the same as for adults.
lvial + diluent: 604.94 MRP